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Most patients with a diagnosis of HSIL are managed with LEEP. Histologic evaluation of LEEP specimens allows con rmation of the diagnosis of HSIL and evaluation for the presence or absence of invasive carcinoma. Reported success rates in treating dysplasia by LEEP range from 60% to 95%, depending on the criteria used to de ne failure. LEEP specimens showing positive margins for HSIL, multiple quadrant involvement by HSIL, and extension of HSIL into endocervical glands have been shown to have higher recurrence rates.35 Pathology reports from LEEP specimens should at a minimum comment on margin status, speci cally designating the positive margin (endocervical, deep radial, or ectocervial) when appropriate. On rare occasion, a patient with biopsy-con rmed HSIL may have a LEEP specimen negative for dysplasia. These patients still need follow-up similar to those with a positive LEEP. Although cytology is good at evaluating cure post-LEEP, HPV testing appears better, with a sensitivity of approximately 95% in identifying patients with recurrent/persistent disease.

As research matured and became less impressionistic the focus shifted towards an understanding of the suffering of all it involved More reliable tools for family observation were employed, on normal as well as clinical families, and researchers became aware of the fact that very few normal family functions remain after living with an eating-disordered person for a year or more The concept of expressed emotion (Leff & Vaughn, 1985) has found its way into eating disorder research (van Furth, 1991; le Grange et al, 1992a) Expressed emotion is a measure of family interaction originally developed in the schizophrenia eld It assesses the attitudes and behaviours that family members express towards their ill relative The interaction in families of eating-disordered patients is characterised by low levels of expressed emotion, and particularly of criticism, as compared to those found in families of schizophrenic patients (Dare et al.

This is because modified Wollaston (Nomarski) prisms have their interference planes located outside the prism itself Rotate the prism between the crossed polars again and notice that there is a unique position giving extinction At this orientation the phase retardation introduced between O and E rays by one slab of the prism is exactly reversed by phase displacements in the other slab, so light emerges plane parallel and vibrating in the same plane as the incident polarized light The resultant rays are blocked by the analyzer, giving extinction In the microscope examine the action of a DIC prism between crossed polars (the other prism has been removed) in the aperture plane using a telescope eyepiece or Bertrand lens A bright field is seen with a dark fringe running across it.

(6,900,505) (7,038,515) (7,179,285) (7,322,871) (7,469,329) (7,618,715) (7,771,089) (7,926,511) (8,085,041) (8,246,742) (8,411,677) (8,579,911) (8,751,509) (8,926,539) (9,105,070) (9,287,171) (9,472,915) (9,662,373) (9,855,620) (10,052,733)

When both prisms are in position and the back aperture is observed, the field looks dark (extinction) because light emerging from each position in the condenser prism is now exactly compensated for by the objective prism All beams emerging from the objective prism are again linearly polarized in the direction of the original polarizer, and thus are blocked by the analyzer (extinction)..

Individual can say or demonstrate no . Individual knows that having intercourse can result in pregnancy. When given options the individual can make an informed choice. Individual knows that having intercourse or other sexual relations can result in obtaining a disease. Individual can differentiate between appropriate and inappropriate times and places to engage in intimate relations. Individual can differentiate between males and females. Individual can recognise individuals or situations which might be a threat to him or her. Individual will stop behaviour if another person tells him or her no.

, 1994; Goldstein, 1981; le Grange et al, 1992a; Hodes et al, 1999; Szmukler et al, 1985; van Furth et al, 1996) However criticism is higher in families of bulimic patients than in those of anorexic patients; it has been argued that this could be a result of the greater disruption and lesser acceptability of the bulimic symptomatology (Hodes & le Grange, 1993) Higher levels of emotional expression have also been associated to other variables such as older age, laxative use, and presence of comorbidity (van Furth et al, 1996) The measure of expressed emotion (EE) in relatives is associated with a poor outcome for patients with eating disorders (see Butzlaff & Hooley, 1998) The effect size of the relationship between living with a relative with high EE (critical, hostile or emotionally overinvolved) and poor outcome is 051.